MCM3 Antikörper (AA 36-64)
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- Target Alle MCM3 Antikörper anzeigen
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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Bindungsspezifität
- AA 36-64
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MCM3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Bovine
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 36-64 from the human protein was used as the immunogen for this MCM3 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MCM3 Primärantikörper
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- Applikationshinweise
- Titration of the MCM3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the MCM3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
- Andere Bezeichnung
- MCM3 (MCM3 Produkte)
- Hintergrund
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].
- UniProt
- P25205
- Pathways
- DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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