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MCM3 Antikörper (AA 36-64)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MCM3 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3031804

Kurzübersicht für MCM3 Antikörper (AA 36-64) (ABIN3031804)

Target

Alle MCM3 Antikörper anzeigen
MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Reaktivität

  • 85
  • 32
  • 26
  • 7
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 77
  • 7
  • 3
Kaninchen

Klonalität

  • 69
  • 18
Polyklonal

Konjugat

  • 48
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MCM3 Antikörper ist unkonjugiert

Applikation

  • 48
  • 29
  • 20
  • 17
  • 16
  • 15
  • 14
  • 14
  • 11
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-64

    Kreuzreaktivität (Details)

    Expected species reactivity: Mouse, Bovine

    Aufreinigung

    Antigen affinity purified

    Immunogen

    A portion of amino acids 36-64 from the human protein was used as the immunogen for this MCM3 antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the MCM3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the MCM3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

    Andere Bezeichnung

    MCM3

    Hintergrund

    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].

    UniProt

    P25205

    Pathways

    DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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