LOXL3 Antikörper (AA 715-744)
Kurzübersicht für LOXL3 Antikörper (AA 715-744) (ABIN3031669)
Target
Alle LOXL3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 715-744
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Verwendungszweck
- LOXL3 Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 715-744 from the human protein was used as the immunogen for this LOXL3 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the LOXL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the LOXL3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))
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Andere Bezeichnung
- LOXL3
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Hintergrund
- This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.
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UniProt
- P58215
Target
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