LIM Domain Kinase 1 Antikörper (AA 479-508)
Kurzübersicht für LIM Domain Kinase 1 Antikörper (AA 479-508) (ABIN3028800)
Target
Alle LIM Domain Kinase 1 (LIMK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 479-508
-
Aufreinigung
- Purified
-
Immunogen
- A portion of amino acids 479-508 from the human protein was used as the immunogen for this LIMK1 antibody.
-
Isotyp
- IgG1 kappa
-
-
-
-
Applikationshinweise
- Titration of the LIMK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the LIMK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- LIM Domain Kinase 1 (LIMK1)
-
Andere Bezeichnung
- LIMK1
-
Hintergrund
- Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
-
UniProt
- P53667
-
Pathways
- Caspase Kaskade in der Apoptose, Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
-