Lamin B1 Antikörper (AA 459-488)

Produktnummer ABIN3031587

Produktdetails anti-Lamin B1 Antikörper

Target: Lamin B1 (LMNB1)

Bindungsspezifität: AA 459-488

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat

Aufreinigung: Purified

Immunogen: A portion of amino acids 459-488 from the human protein was used as the immunogen for this Lamin B1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Lamin B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Lamin B1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Lamin B1

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: Lamin B1 (LMNB1 Produkte)

Hintergrund: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.

UniProt: P20700

Pathways: Apoptose, Caspase Kaskade in der Apoptose