KDM6A Antikörper (C-Term)
Kurzübersicht für KDM6A Antikörper (C-Term) (ABIN3031655)
Target
Alle KDM6A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This mouse Kdm6a antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1041-1074 amino acids from the C-terminal region of mouse Kdm6a.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Kdm6a antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Kdm6a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
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Andere Bezeichnung
- Kdm6a
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Hintergrund
- Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (By similarity).
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UniProt
- O70546
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Pathways
- Tube Formation, Warburg Effekt
Target
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