ISL1 Antikörper (AA 156-185)

Produktnummer ABIN3031505

Produktdetails anti-ISL1 Antikörper

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Bindungsspezifität: AA 156-185

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Rat, Chicken, Zebrafish

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 156-185 from the human protein was used as the immunogen for this ISL1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ISL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ISL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ISL1

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Andere Bezeichnung: ISL1 (ISL1 Produkte)

Synonyme: Xisl-1 antikoerper, Xislet-1 antikoerper, islet1 antikoerper, ISLET-1 antikoerper, ISLET1 antikoerper, Isl-1 antikoerper, islet-1 antikoerper, isl-1=homeobox antikoerper, Islet-1 antikoerper, ISL LIM homeobox 1 S homeolog antikoerper, ISL LIM homeobox 1 antikoerper, ISL1 transcription factor, LIM/homeodomain antikoerper, isl1.S antikoerper, ISL1 antikoerper, Isl1 antikoerper, isl1 antikoerper

Hintergrund: ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding