IL12B Antikörper (AA 264-290)
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- Target Alle IL12B Antikörper anzeigen
- IL12B (Interleukin 12 beta (IL12B))
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Bindungsspezifität
- AA 264-290
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL12B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 264-290 from the human protein was used as the immunogen for this IL-12B antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IL12B Primärantikörper
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anti-Interleukin 12 beta (IL12B) (AA 30-320) antibody
IL12B Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C2 unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-327) antibodyIL12B Reaktivität: Schaf WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-328) antibodyIL12B Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 201-300) antibodyIL12B Reaktivität: Human, Maus WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 264-290), (C-Term) antibodyIL12B Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB28444 unconjugated
anti-Interleukin 12 beta (IL12B) (AA 229-328) antibodyIL12B Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2H6 unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B Reaktivität: Maus, Ratte WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 35-302) antibodyIL12B Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) antibodyIL12B Reaktivität: Human, Schwein ELISA, IHC (fro) Wirt: Maus Monoclonal I-1A4 unconjugated
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- Applikationshinweise
- Titration of the IL-12B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Western blot: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the IL-12B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- IL12B (Interleukin 12 beta (IL12B))
- Andere Bezeichnung
- IL-12B (IL12B Produkte)
- Hintergrund
- IL12B is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
- UniProt
- P29460
- Pathways
- JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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