HSP90 Antikörper (AA 150-400)
Kurzübersicht für HSP90 Antikörper (AA 150-400) (ABIN3031170)
Target
Alle HSP90 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 150-400
-
Verwendungszweck
- HSP90 Antibody / HSP90AA1
-
Aufreinigung
- Purified
-
Immunogen
- A portion of amino acids from 150-400 of the human protein were used as the immunogen for this HSP90AA1 antibody.
-
Isotyp
- IgG1, lambda
-
-
-
-
Applikationshinweise
- Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the HSP90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- HSP90 (Heat Shock Protein 90 (HSP90))
-
Andere Bezeichnung
- HSP90
-
Hintergrund
- Heat Shock Protein 90 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt]
-
UniProt
- P07900
-
Pathways
- M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
Target
-