HSP90
Reaktivität: Human
WB, IP, IHC, ELISA, IF, ICC, AA
Wirt: Maus
Monoclonal
H9010
APC
Applikationshinweise
Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the HSP90 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
HSP90
(Heat Shock Protein 90 (HSP90))
Andere Bezeichnung
HSP90
Hintergrund
Heat Shock Protein 90 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt]