HOPX Antikörper (AA 22-54)
Kurzübersicht für HOPX Antikörper (AA 22-54) (ABIN3031254)
Target
Alle HOPX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 22-54
-
Verwendungszweck
- Hopx Antibody
-
Aufreinigung
- Antigen affinity
-
Immunogen
- This mouse Hopx antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of mouse Hopx.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the Hopx antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the Hopx antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- HOPX (HOP Homeobox (HOPX))
-
Andere Bezeichnung
- Hopx
-
Hintergrund
- Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.
-
UniProt
- Q8R1H0
-
Pathways
- Regulation of Muscle Cell Differentiation
Target
-