HMGB1 Antikörper (AA 152-180)

Produktnummer ABIN3031204

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HMGB1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HMGB1 Antikörper (AA 152-180) (ABIN3031204)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HMGB1 Antikörper

Bindungsspezifität: AA 152-180

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig, Primate, Hamster

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 152-180 from the human protein was used as the immunogen for this HMGB-1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the HMGB-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the HMGB-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu HMGB1

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Andere Bezeichnung: HMGB-1

Hintergrund: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). [UniProt]

UniProt: P09429

Pathways: p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome