HES1 Antikörper (AA 102-137)
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- Target Alle HES1 Antikörper anzeigen
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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Bindungsspezifität
- AA 102-137
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HES1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität (Details)
- Expected species reactivity: Bovine, Human, Rat, Xenopus
- Aufreinigung
- Antigen affinity purified
- Immunogen
- This mouse Hes1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of mouse Hes1.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product HES1 Primärantikörper
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- Applikationshinweise
- Titration of the Hes1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the Hes1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- Andere Bezeichnung
- Hes1 (HES1 Produkte)
- Synonyme
- HES-1 antikoerper, HHL antikoerper, HRY antikoerper, bHLHb39 antikoerper, Hry antikoerper, HAIRY1 antikoerper, c-hairy1A antikoerper, Xhairy1 antikoerper, hairy1 antikoerper, hes1 antikoerper, Xhairy-1 antikoerper, Xlh1 antikoerper, hes family bHLH transcription factor 1 antikoerper, hairy and enhancer of split 1 (Drosophila) antikoerper, hes family bHLH transcription factor 4 antikoerper, hes family bHLH transcription factor 1 S homeolog antikoerper, hes family bHLH transcription factor 1 L homeolog antikoerper, HES1 antikoerper, Hes1 antikoerper, HES4 antikoerper, hes1.S antikoerper, hes1.L antikoerper
- Hintergrund
- Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
- UniProt
- P35428
- Pathways
- DNA Reparatur
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