GRB2 Antikörper (AA 187-216)
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- Target Alle GRB2 Antikörper anzeigen
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
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Bindungsspezifität
- AA 187-216
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Chicken, Xenopus
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 187-216 from the human protein was used as the immunogen for this GRB2 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product GRB2 Primärantikörper
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- Applikationshinweise
- Titration of the GRB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the GRB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- Andere Bezeichnung
- GRB2 (GRB2 Produkte)
- Hintergrund
- GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
- UniProt
- P62993
- Pathways
- RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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