Osteoactivin Antikörper (AA 541-569)

Produktnummer ABIN3032103

Produktdetails anti-Osteoactivin Antikörper

Target: Osteoactivin (GPNMB)

Bindungsspezifität: AA 541-569

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Osteoactivin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 541-569 from the human protein was used as the immunogen for this GPNMB antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the GPNMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the GPNMB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Osteoactivin

Target: Osteoactivin (GPNMB)

Andere Bezeichnung: GPNMB (GPNMB Produkte)

Synonyme: HGFIN antikoerper, NMB antikoerper, DC-HIL antikoerper, Dchil antikoerper, ipd antikoerper, glycoprotein nmb antikoerper, glycoprotein (transmembrane) nmb antikoerper, glycoprotein nmb L homeolog antikoerper, Gpnmb antikoerper, GPNMB antikoerper, gpnmb.L antikoerper

Hintergrund: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: Q14956