EZH1 Antikörper (AA 393-422)

Produktnummer ABIN3030806

Der Kaninchen Polyklonal Anti-EZH1-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, EZH1 in Proben von Human zu detektieren.

Kurzübersicht für EZH1 Antikörper (AA 393-422) (ABIN3030806)

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EZH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-EZH1 Antikörper

Bindungsspezifität: AA 393-422

Kreuzreaktivität (Details): Expected species reactivity: Bovine

Aufreinigung: Purified

Immunogen: A portion of amino acids 393-422 from the human protein was used as the immunogen for this EZH1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the EZH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the EZH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu EZH1

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Andere Bezeichnung: EZH1

Hintergrund: EZH1 encodes a protein of 747 amino acids that displays 55 % amino acid identity overall with the Drosophila homolog.1 The strong sequence conservation suggested potential roles for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that preserve heterochromatin stability. EZH1 is expressed as 2 major transcripts in all adult and fetal human tissues evaluated. Analysis of an EZH1 cDNA revealed an unusual splicing event involving EZH1 and a tandemly linked gene GPR2 and suggested a potential mechanism for modifying the EZH1 protein in the conserved C-terminal domain. The GPR2 gene maps to 17q21.1-q21.3 in the vicinity of the BRCA1 gene.

UniProt: Q92800