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Endothelin 3 Antikörper (AA 168-197)

This anti-Endothelin 3 antibody (ABIN3030805) is a Rabbit Polyclonal antibody detecting Endothelin 3 in WB, ELISA. Suitable for Human.
Produktnummer ABIN3030805

Kurzübersicht für Endothelin 3 Antikörper (AA 168-197) (ABIN3030805)

Target

Alle Endothelin 3 (EDN3) Antikörper anzeigen
Endothelin 3 (EDN3)

Reaktivität

  • 32
  • 6
  • 4
  • 2
  • 2
  • 1
Human

Wirt

  • 33
  • 3
Kaninchen

Klonalität

  • 34
  • 2
Polyklonal

Konjugat

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation

  • 24
  • 12
  • 8
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 168-197

    Aufreinigung

    Antigen affinity purified

    Immunogen

    A portion of amino acids 168-197 from the human protein was used as the immunogen for this EDN3 antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the EDN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the EDN3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Endothelin 3 (EDN3)

    Andere Bezeichnung

    EDN3

    Hintergrund

    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

    UniProt

    P14138

    Pathways

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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