RCAN1 Antikörper (AA 222-252)

Produktnummer ABIN3032453

Der Kaninchen Polyklonal Anti-RCAN1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, RCAN1 in Proben von Human zu detektieren.

Kurzübersicht für RCAN1 Antikörper (AA 222-252) (ABIN3032453)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RCAN1 Antikörper

Bindungsspezifität: AA 222-252

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Bovine, Hamster

Aufreinigung: Purified

Immunogen: A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: DSCR1

Hintergrund: DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development