DNMT3A Antikörper (AA 723-752)
Kurzübersicht für DNMT3A Antikörper (AA 723-752) (ABIN3030749)
Target
Alle DNMT3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 723-752
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Verwendungszweck
- Dnmt3a Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 723-752 from the human protein was used as the immunogen for this Dnmt3a antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Dnmt3a antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Dnmt3a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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Andere Bezeichnung
- Dnmt3a
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Hintergrund
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
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UniProt
- Q9Y6K1
Target
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