Claudin 2 Antikörper (AA 135-164)

Produktnummer ABIN3030535

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Claudin 2 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Claudin 2 Antikörper (AA 135-164) (ABIN3030535)

Target: Claudin 2 (CLDN2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Claudin 2 Antikörper

Bindungsspezifität: AA 135-164

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Bovine

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 135-164 from the human protein was used as the immunogen for this Claudin 2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Claudin 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Claudin 2

Target: Claudin 2 (CLDN2)

Hintergrund: Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. Mice that are deficient in the protein have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. Similar results have been obtained with cultured cells, as overexpression in CLDN2 lacking cells leads to increase of permeability for small cations. Furthermore, CLDN2 has been shown to form paracellular channels for water. [Wiki]

UniProt: P57739

Pathways: Hepatitis C