CD3 epsilon Antikörper (AA 154-182)
Kurzübersicht für CD3 epsilon Antikörper (AA 154-182) (ABIN3030389)
Target
Alle CD3 epsilon (CD3E) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 154-182
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Kreuzreaktivität (Details)
- Expected species reactivity: Primate
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 154-182 from the human protein was used as the immunogen for this CD3e antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the CD3e antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CD3e antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD3 epsilon (CD3E)
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Andere Bezeichnung
- CD3e
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Hintergrund
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
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UniProt
- P07766
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Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Target
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