CD3 epsilon Antikörper (AA 154-182)

Produktnummer ABIN3030389

Der Kaninchen Polyklonal Anti-CD3 epsilon-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CD3 epsilon in Proben von Human zu detektieren.

Kurzübersicht für CD3 epsilon Antikörper (AA 154-182) (ABIN3030389)

Target: CD3 epsilon (CD3E)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD3 epsilon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD3 epsilon Antikörper

Bindungsspezifität: AA 154-182

Kreuzreaktivität (Details): Expected species reactivity: Primate

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 154-182 from the human protein was used as the immunogen for this CD3e antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CD3e antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CD3e antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CD3 epsilon

Target: CD3 epsilon (CD3E)

Andere Bezeichnung: CD3e

Hintergrund: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway