Caspase 10 Antikörper (AA 164-192)

Produktnummer ABIN3030290

Der Kaninchen Polyklonal Anti-Caspase 10-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Caspase 10 in Proben von Human zu detektieren.

Kurzübersicht für Caspase 10 Antikörper (AA 164-192) (ABIN3030290)

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Caspase 10 Antikörper

Bindungsspezifität: AA 164-192

Aufreinigung: Purified

Immunogen: A portion of amino acids 164-192 from the human protein was used as the immunogen for this Caspase-10 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Caspase-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Caspase-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Caspase 10

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Andere Bezeichnung: Caspase-10

Hintergrund: CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.

UniProt: Q92851

Pathways: Apoptose, Caspase Kaskade in der Apoptose