C5 Antikörper (AA 253-281)

Produktnummer ABIN3029690

Der Kaninchen Polyklonal Anti-C5-Antikörper wurde für WB, ELISA, IHC und FACS validiert. Er ist geeignet, C5 in Proben von Human zu detektieren.

Kurzübersicht für C5 Antikörper (AA 253-281) (ABIN3029690)

Target: C5 (Complement Component 5 (C5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-C5 Antikörper

Bindungsspezifität: AA 253-281

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 253-281 from the human protein was used as the immunogen for this C5 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the C5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the C5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu C5

Target: C5 (Complement Component 5 (C5))

Andere Bezeichnung: C5

Hintergrund: C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.

UniProt: P01031

Pathways: Komplementsystem, Carbohydrate Homeostasis