BMPR1A Antikörper (AA 166-196)
Kurzübersicht für BMPR1A Antikörper (AA 166-196) (ABIN3030183)
Target
Alle BMPR1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 166-196
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 166-196 from the human protein was used as the immunogen for this BMPR1A antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the BMPR1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the BMPR1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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Andere Bezeichnung
- BMPR1A
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Hintergrund
- The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
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UniProt
- P36894
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Pathways
- Stem Cell Maintenance
Target
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