BMP1 Antikörper (AA 957-986)

Produktnummer ABIN3030175

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BMP1 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für BMP1 Antikörper (AA 957-986) (ABIN3030175)

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-BMP1 Antikörper

Bindungsspezifität: AA 957-986

Aufreinigung: Purified

Immunogen: A portion of amino acids 957-986 from the human protein was used as the immunogen for this BMP1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the BMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the BMP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu BMP1

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Andere Bezeichnung: BMP1

Hintergrund: The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.

UniProt: P13497

Pathways: Lipid Metabolism