Aurora Kinase B Antikörper (AA 84-111)

Produktnummer ABIN3030074

Der Kaninchen Polyklonal anti-Aurora Kinase B Antikörper wird verwendet zum Nachweis von Aurora Kinase B in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Aurora Kinase B Antikörper (AA 84-111) (ABIN3030074)

Target: Aurora Kinase B (AURKB)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora Kinase B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Aurora Kinase B Antikörper

Bindungsspezifität: AA 84-111

Kreuzreaktivität (Details): Expected species reactivity: Rat

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 84-111 from the mouse protein was used as the immunogen for this Aurkb antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Aurkb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Aurkb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Andere Bezeichnung: Aurkb

Hintergrund: Aurkb may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1 (By similarity).

UniProt: O70126

Pathways: T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades