Androgen Receptor Antikörper (AA 475-504)

Produktnummer ABIN3029943

Dieses Anti-Androgen Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Androgen Receptor in WB und ELISA. Geeignet für Human.

Kurzübersicht für Androgen Receptor Antikörper (AA 475-504) (ABIN3029943)

Target: Androgen Receptor (AR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Androgen Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Androgen Receptor Antikörper

Bindungsspezifität: AA 475-504

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 475-504 from the human protein was used as the immunogen for this AR antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the AR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the AR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Androgen Receptor

Target: Androgen Receptor (AR)

Andere Bezeichnung: AR

Hintergrund: The androgen receptor, also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding either of the androgenic hormones, testosterone, or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. It is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor.
The main function of the AR is as a DNA-binding transcription factor that regulates gene expression, however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. [Wiki]

UniProt: P10275

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding