ErbB2/Her2 Antikörper (AA 1227-1255)
Kurzübersicht für ErbB2/Her2 Antikörper (AA 1227-1255) (ABIN3029510)
Target
Alle ErbB2/Her2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1227-1255
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Verwendungszweck
- Anti-HER2 Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 1227-1255 from the human protein was used as the immunogen for this anti-HER2 antibody.
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Isotyp
- Ig Fraction
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anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 23-372) antibody
ErbB2/Her2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1248) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr877) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1112) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 Reaktivität: Human WB, IF, ELISA, IHC (p), PLA Wirt: Maus Monoclonal 3B1 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte, Hund, Affe, Pferd, Schwein, Rind (Kuh), Kaninchen, Hamster, Avian, Cat, Huhn, Esel, Ziege, Meerschweinchen, Schaf WB, IHC (p), IHC (fro) Wirt: Ziege Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reaktivität: Human IHC, IF, FACS Wirt: Maus Monoclonal ERBB2-2452 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reaktivität: Human IHC Wirt: Maus Monoclonal ERBB2-3078 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 1205-1255) antibodyErbB2/Her2 Reaktivität: Human, Maus WB, IHC, FACS, IP, ICC Wirt: Kaninchen Monoclonal BLR241L unconjugated Recombinant Antibody
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 Reaktivität: Human WB, IF, ELISA, IHC (p) Wirt: Maus Monoclonal 4E1 unconjugated
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Applikationshinweise
- Titration of the anti-HER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the anti-HER2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Andere Bezeichnung
- HER2
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Hintergrund
- HER2/ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
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UniProt
- P04626
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
Target
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