ErbB2/Her2 Antikörper (AA 1227-1255)
Kurzübersicht für ErbB2/Her2 Antikörper (AA 1227-1255) (ABIN3029510)
Target
Alle ErbB2/Her2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 1227-1255
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                                            Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
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                                            Aufreinigung
- Antigen affinity purified
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                                            Immunogen
- A portion of amino acids 1227-1255 from the human protein was used as the immunogen for this anti-HER2 antibody.
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                                            Isotyp
- Ig Fraction
 
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                                            Applikationshinweise
- Titration of the anti-HER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Aliquot the anti-HER2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
 
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    - ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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                                            Andere Bezeichnung
- HER2
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                                            Hintergrund
- HER2/ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
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                                            UniProt
- P04626
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                                            Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
 Target
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