ALK Antikörper (AA 636-666)

Produktnummer ABIN3029939

Der Kaninchen Polyklonal anti-ALK Antikörper wird verwendet zum Nachweis von ALK in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für ALK Antikörper (AA 636-666) (ABIN3029939)

Target: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ALK Antikörper

Bindungsspezifität: AA 636-666

Aufreinigung: Purified

Immunogen: A portion of amino acids 636-666 from the human protein was used as the immunogen for this ALK antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ALK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ALK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ALK

Target: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Andere Bezeichnung: ALK

Hintergrund: Anaplastic lymphoma kinase, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2,5)(p23,q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.

UniProt: Q9UM73

Pathways: RTK Signalweg