HDAC6 Antikörper

Produktnummer ABIN4953258

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HDAC6 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HDAC6 Antikörper (ABIN4953258)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HDAC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 3B2-F5-G6

Produktdetails anti-HDAC6 Antikörper

Aufreinigung: Protein G affinity

Immunogen: A human recombinant protein was used as the immunogen for this HDAC6 antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Lagerung: -20 °C

Informationen zur Lagerung: Store the HDAC6 antibody at -20°C.

Details zu HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Andere Bezeichnung: HDAC6

Hintergrund: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [UniProt]

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling