EIF4E Antikörper
Kurzübersicht für EIF4E Antikörper (ABIN4953242)
Target
Alle EIF4E Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Aufreinigung
- Protein G affinity
-
Immunogen
- A human recombinant protein was used as the immunogen for this EIF4E antibody.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the EIF4E antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store the EIF4E antibody at -20°C.
-
-
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
-
Andere Bezeichnung
- EIF4E
-
Hintergrund
- Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [UniProt]
-
UniProt
- P06730
-
Pathways
- BCR Signaling
Target
-