PKC eta Antikörper (AA 30-389)

Produktnummer ABIN4952175

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PKC eta in WB und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PKC eta Antikörper (AA 30-389) (ABIN4952175)

Target: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC eta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-PKC eta Antikörper

Bindungsspezifität: AA 30-389

Aufreinigung: Antigen affinity

Immunogen: Amino acids 30-389 of human PKC eta were used as the immunogen for the PKC eta antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PKC eta antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,FACS: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the PKC eta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PKC eta

Target: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Andere Bezeichnung: PKC eta

Hintergrund: PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

UniProt: P24723

Pathways: Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling