Lamin B1 Antikörper (AA 266-583)

Produktnummer ABIN4951627

Der Kaninchen Polyklonal Anti-Lamin B1-Antikörper wurde für WB, ICC, IHC (p) und IHC (fro) validiert. Er ist geeignet, Lamin B1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Lamin B1 Antikörper (AA 266-583) (ABIN4951627)

Target: Lamin B1 (LMNB1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Lamin B1 Antikörper

Bindungsspezifität: AA 266-583

Aufreinigung: Antigen affinity

Immunogen: Amino acids 266-583 of human Lamin B1 were used as the immunogen for the LMNB1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the LMNB1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,ICC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the LMNB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Lamin B1

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: Lamin B1

Hintergrund: Lamin B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

UniProt: P20700

Pathways: Apoptose, Caspase Kaskade in der Apoptose