Villin 1 Antikörper (AA 179-311)

Produktnummer ABIN4949934

Dieser Maus Monoklonal Antikörper detektiert spezifisch Villin 1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Villin 1 Antikörper (AA 179-311) (ABIN4949934)

Target: Villin 1 (VIL1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Villin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: VIL1-1314

Produktdetails anti-Villin 1 Antikörper

Bindungsspezifität: AA 179-311

Verwendungszweck: Villin Antibody / VIL1 (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 179-311 from the human protein were used as the immunogen for this Villin antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Titration of the Villin antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Villin 1

Target: Villin 1 (VIL1)

Andere Bezeichnung: Villin

Hintergrund: Recognizes a protein of ~93 kDa which is identified as Villin (VIL1). It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, Villin is predominantly expressed in tumors of colorectal origin. Antibody to Villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization