Villin 1 Antikörper (AA 179-311)

Produktnummer ABIN4949934

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Villin 1 in WB, IF, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Villin 1 Antikörper (AA 179-311) (ABIN4949934)

Target: Villin 1 (VIL1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Villin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: VIL1-1314

Produktdetails anti-Villin 1 Antikörper

Bindungsspezifität: AA 179-311

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 179-311 from the human protein were used as the immunogen for this Villin antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Titration of the Villin antibody may be required for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 0.25-0.5 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Villin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Villin 1

Target: Villin 1 (VIL1)

Andere Bezeichnung: Villin

Hintergrund: Recognizes a protein of ~93  kDa which is identified as Villin (VIL1). It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, Villin is predominantly expressed in tumors of colorectal origin. Antibody to Villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization