Podoplanin Antikörper (AA 24-126)

Produktnummer ABIN4949854

Der Maus Monoklonal anti-Podoplanin Antikörper wird verwendet zum Nachweis von Podoplanin in Proben von Human. Er wurde validiert für WB, FACS, IF und IHC (p).

Kurzübersicht für Podoplanin Antikörper (AA 24-126) (ABIN4949854)

Target: Podoplanin (PDPN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Podoplanin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PDPN-1433

Produktdetails anti-Podoplanin Antikörper

Bindungsspezifität: AA 24-126

Aufreinigung: Protein G affinity chromatography

Immunogen: A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Podoplanin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 0.5-1 μg/mL,FACS: 0.5-1 μg/million cells in 0.1ml,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Podoplanin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Podoplanin

Target: Podoplanin (PDPN)

Andere Bezeichnung: Podoplanin / gp36

Hintergrund: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Pathways: Dicarboxylic Acid Transport