MMP2 Antikörper (AA 195-319)

Produktnummer ABIN4949794

Der Maus Monoklonal Anti-MMP2-Antikörper wurde für WB validiert. Er ist geeignet, MMP2 in Proben von Human zu detektieren.

Kurzübersicht für MMP2 Antikörper (AA 195-319) (ABIN4949794)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: MMP2-1501

Produktdetails anti-MMP2 Antikörper

Bindungsspezifität: AA 195-319

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 195-319 were used as the immunogen for the MMP2 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the MMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2

Hintergrund: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.

Pathways: Activation of Innate immune Response