LHCGR Antikörper (N-Term)

Produktnummer ABIN4949739

Produktdetails anti-LHCGR Antikörper

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LHCGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: Protein G affinity chromatography

Immunogen: A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.

Klon: LHCGR-1415

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the hCG Receptor antibody should be determined by the researcher.\. FACS: 0.5-1 μg/million cells in 0.1ml,IF: 1-2 μg/mL,WB: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the hCG Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu LHCGR

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Andere Bezeichnung: hCG Receptor / LH Receptor (LHCGR Produkte)

Synonyme: HHG antikoerper, LCGR antikoerper, LGR2 antikoerper, LH/CG-R antikoerper, LH/CGR antikoerper, LHR antikoerper, LHRHR antikoerper, LSH-R antikoerper, ULG5 antikoerper, Gpcr19-rs1 antikoerper, LH-R antikoerper, Lhr antikoerper, LSHR antikoerper, lhr antikoerper, GTHR-II antikoerper, zfGTHR-II antikoerper, LHCGR antikoerper, LOC100222883 antikoerper, lh-r antikoerper, LOC100305044 antikoerper, luteinizing hormone/choriogonadotropin receptor antikoerper, luteinizing hormone/choriogonadotropin receptor L homeolog antikoerper, luteinizing hormone receptor antikoerper, LHCGR antikoerper, Lhcgr antikoerper, lhcgr antikoerper, lhcgr.L antikoerper, lhr antikoerper, LOC100305044 antikoerper

Hintergrund: Recognizes a protein of 78-85  kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling