EPO Antikörper

Produktnummer ABIN4949653

Der Maus Monoklonal Anti-EPO-Antikörper wurde für FACS, IF und IHC (p) validiert. Er ist geeignet, EPO in Proben von Human zu detektieren.

Kurzübersicht für EPO Antikörper (ABIN4949653)

Target: EPO (Erythropoietin (EPO))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPO Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: EPO-1367

Produktdetails anti-EPO Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: A human partial recombinant protein was used as the immunogen for the Erythropoietin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titering of the Erythropoietin antibody may be required for optimal performance.\. IF: 1-2 μg/mL,Immunohistochemistry (FFPE): 4-8 μg/mL for 30 min at RT,Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Erythropoietin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu EPO

Target: EPO (Erythropoietin (EPO))

Andere Bezeichnung: Erythropoietin / EPO

Substanzklasse: Hormone

Hintergrund: Erythropoietin / EPO is a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. It is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. Erythropoietin is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis.

Pathways: JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity