CD80 Antikörper
Kurzübersicht für CD80 Antikörper (ABIN4949540)
Target
Alle CD80 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD80 Antibody / B7-1 (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Recombinant human protein used as the immunogen for the CD80 antibody.
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Isotyp
- IgG1, kappa
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anti-CD80 (CD80) (AA 35-244) antibody
CD80 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD80 (CD80) (AA 35-246) antibodyCD80 Reaktivität: Human FACS, WB, IHC Wirt: Kaninchen Monoclonal BLR206K unconjugated Recombinant Antibody
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PerCP
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 FITC
anti-CD80 (CD80) (AA 35-288) antibodyCD80 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reaktivität: Maus FACS, WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD80 (CD80) (AA 37-245) antibodyCD80 Reaktivität: Maus FACS, WB, ICC Wirt: Kaninchen Monoclonal BLR237K unconjugated Recombinant Antibody
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD80 (CD80) antibodyCD80 Reaktivität: Maus, Hund FACS, IP, IHC (fro) Wirt: Armenischer Hamster Monoclonal 16-10A1 unconjugated
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Applikationshinweise
- Optimal dilution of the CD80 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the CD80 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD80
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Andere Bezeichnung
- CD80
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Hintergrund
- T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
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UniProt
- P33681
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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