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beta Catenin Antikörper (N-Term)

Der Maus Monoklonal Anti-beta Catenin-Antikörper wurde für WB, FACS und IF validiert. Er ist geeignet, beta Catenin in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN4949461

Kurzübersicht für beta Catenin Antikörper (N-Term) (ABIN4949461)

Target

Alle beta Catenin (CATNB) Antikörper anzeigen
beta Catenin (CATNB) (Catenin, beta (CATNB))

Reaktivität

  • 350
  • 240
  • 219
  • 30
  • 22
  • 21
  • 18
  • 18
  • 7
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 272
  • 81
  • 4
  • 1
  • 1
Maus

Klonalität

  • 251
  • 106
  • 2
Monoklonal

Konjugat

  • 124
  • 24
  • 11
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 1
  • 1
  • 1
Dieser beta Catenin Antikörper ist unkonjugiert

Applikation

  • 224
  • 171
  • 120
  • 118
  • 101
  • 81
  • 67
  • 46
  • 37
  • 36
  • 31
  • 26
  • 8
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon

12F7
  • Bindungsspezifität

    • 44
    • 28
    • 23
    • 20
    • 20
    • 19
    • 17
    • 17
    • 16
    • 16
    • 16
    • 15
    • 8
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Aufreinigung

    Protein G affinity chromatography

    Immunogen

    A recombinant fusion protein consisting of the N-terminal half of human beta-Catenin fused to maltose binding protein was used as the immunogen for the Beta Catenin antibody.

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Titration of the Beta Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,WB: 1-2 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Konservierungsmittel

    Azide free

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store the Beta Catenin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    Andere Bezeichnung

    Beta Catenin

    Hintergrund

    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]

    Pathways

    Peptide Hormone Metabolism
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