PLIN2
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Titering of the ADRP antibody may be required for optimal performance.\. ELISA: order formulation without BSA for coating,IHC (FFPE): 2-4 μg/mL,IF: 1-2 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
The ADRP antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Target
ADRP (PLIN2)
(Perilipin 2 (PLIN2))
Andere Bezeichnung
Adipophilin / Perilipin 2 / ADRP / PLIN2
Hintergrund
Adipophilin, also called Perilipin 2, ADRP (Adipose differentiation related protein), and PLIN2, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material and maybe involved in development and maintenance of adipose tissue. It is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.