Nkx2-2 Antikörper

Produktnummer ABIN4949366

Dieses Anti-Nkx2-2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Nkx2-2 in IF, FACS und IHC (p). Geeignet für Human.

Kurzübersicht für Nkx2-2 Antikörper (ABIN4949366)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nkx2-2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Nkx2-2 Antikörper

Aufreinigung: Protein A affinity chromatography

Immunogen: A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titering of the NKX2.2 antibody may be required for optimal performance.\. FACS: 0.5-1 μg/10e6 cells in 0.1ml,IF: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 minutes at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the NKX2.2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Andere Bezeichnung: NKX2.2

Hintergrund: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

Gen-ID: 4821

Pathways: Dopaminergic Neurogenesis