HAX1 Antikörper (N-Term)

Produktnummer ABIN492528

Dieses Anti-HAX1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von HAX1 in WB und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für HAX1 Antikörper (N-Term) (ABIN492528)

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HAX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 8F9G7

Produktdetails anti-HAX1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.

Produktmerkmale: Synonyms: HAX-1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-bindingprotein 1

Aufreinigung: Immunoaffinity Chromotography.

Immunogen: A 15 amino acid peptide near the amino terminus of Human Hax1a (GenBank accession no. NP_006109).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: Hax1a antibody can be used for detection of Hax1a at 1-2 μg/mL. Positive Control: Human brain tissue lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Andere Bezeichnung: HAX1

Hintergrund: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1

Gen-ID: 10456

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization