TLE4 Antikörper

Produktnummer ABIN4914677

This anti-TLE4 antibody (ABIN4914677) is a Mouse Monoclonal antibody detecting TLE4 in WB. Suitable for Human.

Kurzübersicht für TLE4 Antikörper (ABIN4914677)

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TLE4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 4C4

Produktdetails anti-TLE4 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TLE4

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Andere Bezeichnung: TLE4

Hintergrund:

Synonyms: ESG, BCE1, ESG4, GRG4, BCE-1, Grg-4, E(spI), Transducin-like enhancer protein 4, Groucho-related protein 4, TLE4, KIAA1261

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).

Gen-ID: 7091

UniProt: Q04727

Pathways: WNT Signalweg