MAGED1 Antikörper

Produktnummer ABIN4911723

Dieses Anti-MAGED1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MAGED1 in WB. Geeignet für Human.

Kurzübersicht für MAGED1 Antikörper (ABIN4911723)

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAGED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 5C7

Produktdetails anti-MAGED1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Andere Bezeichnung: MAGED1

Hintergrund:

Synonyms: NRAGE, DLXIN-1, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, MAGED1, PP2250, PRO2292

Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Gen-ID: 9500

UniProt: Q9Y5V3

Pathways: Neurotrophin Signalübertragung