FGFR2 Antikörper (AA 809-821)

Produktnummer ABIN490845

Dieses Anti-FGFR2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FGFR2 in WB, IHC, IHC (p) und IP. Geeignet für Human.

Kurzübersicht für FGFR2 Antikörper (AA 809-821) (ABIN490845)

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Produktdetails anti-FGFR2 Antikörper

Bindungsspezifität: AA 809-821

Spezifität: FGFR2, Cytoplasmic reacts specifically with FGFR2 using immunoblotting and immunoprecipitation (doublet at 115-125kD) using whole cell lysates of transfected 293T cells, a human, embryonic kidney cell line, expressing recombinant human FGFR2. No reaction with human FGFR1 and FGFR3 is detected. Species cross-reactivity: Human. Expected to cross-react with Mouse (92 % identity with immunogen) and Rat (92 % identity with immunogen) due to sequence homology.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Horse (92%) Panda, Bovine, Dog (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide: KLPQYPHIGSVKT conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 809-821 of the cytoplasmic region of Human FGFR2. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Horse (92%), Panda, Bovine, Dog (85%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P, IP (1:2000), WB (1:2000)

Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Immunohistochemistry (trypsin or protease-digested, formalin-fixed, paraffin-embedded tissue):1:250, Immunoprecipitation: 1:2000, Western Blot:1:2000. Positive control: 293T, embryonic kidney cell line.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 1 % BSA, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu FGFR2

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Andere Bezeichnung: FGF Receptor / FGFR2

Hintergrund: Name/Gene ID: FGFR2
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR2, BEK, BBDS, Bacteria-expressed kinase, CD332 antigen, CFD1, Craniofacial dysostosis 1, CEK3, Fgf bek, FGF receptor, Hydroxyaryl-protein kinase, Jackson-Weiss syndrome, JWS, FGF Receptor 2, KSAM, KGFR, Soluble FGFR4 variant 4, BFR-1, TK14, TK25, CD332, ECT1, K-SAM

Gen-ID: 2263

UniProt: P21802

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding