CDK5 Antikörper

Produktnummer ABIN4907877

Dieses Anti-CDK5-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CDK5 in WB. Geeignet für Human und Maus.

Kurzübersicht für CDK5 Antikörper (ABIN4907877)

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1C9

Produktdetails anti-CDK5 Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein G.

Immunogen: This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 160-286 amino acids from human.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CDK5

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Andere Bezeichnung: CDK5

Hintergrund:

Synonyms: LIS7, PSSALRE, Cyclin-dependent-like kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit, CDK5, CDKN5

Background: This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Gen-ID: 1020

UniProt: Q00535

Pathways: Zellzyklus, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis