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- Target Alle ATG4D Antikörper anzeigen
- ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ATG4D Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Aufreinigung
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogen
- This ATG4D monoclonal antibody is generated from mouse immunized with ATG4D recombinant protein.
- Klon
- 2C1
- Isotyp
- IgG1
- Top Product
- Discover our top product ATG4D Primärantikörper
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anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 441-470), (C-Term) antibody
ATG4D Reaktivität: Human WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB7567 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43) antibodyATG4D Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 220-249) antibodyATG4D Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB7565 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43), (N-Term) antibodyATG4D Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB7563 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 381-474) antibodyATG4D Reaktivität: Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 42-71), (N-Term) antibodyATG4D Reaktivität: Maus WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB14788 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (C-Term) antibodyATG4D Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 227-257) antibodyATG4D Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) antibodyATG4D Reaktivität: Human WB, IF Wirt: Maus Monoclonal 222CT15-4-1 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 326-356) antibodyATG4D Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB11866 unconjugated
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- Applikationshinweise
- WB 1:300-5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
- Andere Bezeichnung
- ATG4D (ATG4D Produkte)
- Hintergrund
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Synonyms: APG4D, AUTL4, APG4-D, Cysteine protease ATG4D, AUT-like 4 cysteine endopeptidase, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, ATG4D
Background: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
- Gen-ID
- 84971
- UniProt
- Q86TL0
- Pathways
- Autophagie
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